RNA-seq of heart: Telomerase Is Essential for Zebrafish Heart Regeneration
Case Control
10.1016/j.celrep.2015.07.064
GSE71755
Unlike human hearts, zebrafish hearts efficiently regenerate after injury. Regeneration is driven by the strong proliferation response of its cardiomyocytes to injury. In this study, we show that active telomerase is required for cardiomyocyte proliferation and full organ recovery, supporting the potential of telomerase therapy as a means of stimulating cell proliferation upon myocardial infarction.
True
mickael.dong
Jan. 9, 2018, 6:05 a.m.
Oct. 23, 2018, 12:37 a.m.
| Biosample ID | Series | biosample_type | biosample_lab | genetic_background | stage | Controlled By | anatomical_term | Hours Post Fertilization |
|---|---|---|---|---|---|---|---|---|
| DCD007058BS | DCD000388SR | tissue | Gomez Lab, CNIC | AB | 90 Days-2 Years | heart | adult |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002068AA | DCD013659BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002445SQ | DCD002457TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002069AA | DCD013660BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002446SQ | DCD002458TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002070AA | DCD013661BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002447SQ | DCD002459TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002071AA | DCD013662BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002448SQ | DCD002460TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Biosample ID | Series | biosample_type | biosample_lab | genetic_background | stage | Controlled By | anatomical_term | Treatment | Hours Post Fertilization |
|---|---|---|---|---|---|---|---|---|---|
| DCD007059BS | DCD000388SR | tissue | Gomez Lab, CNIC | AB | 90 Days-2 Years | DCD007058BS | heart | — | adult |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002072AA | DCD013663BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002450SQ | DCD002462TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002449SQ | DCD002461TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002073AA | DCD013664BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002452SQ | DCD002464TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002451SQ | DCD002463TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002074AA | DCD013665BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002454SQ | DCD002466TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002453SQ | DCD002465TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002075AA | DCD013666BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002455SQ | DCD002467TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Biosample ID | Series | biosample_type | biosample_lab | genetic_background | stage | Controlled By | anatomical_term | Treatment | Hours Post Fertilization | Mutation Description |
|---|---|---|---|---|---|---|---|---|---|---|
| DCD007060BS | DCD000388SR | tissue | Gomez Lab, CNIC | AB | 90 Days-2 Years | DCD007059BS | heart | cryoinjury | adult | — |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002076AA | DCD013667BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002456SQ | DCD002468TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002077AA | DCD013668BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002457SQ | DCD002469TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002078AA | DCD013669BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002458SQ | DCD002470TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002079AA | DCD013670BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002459SQ | DCD002471TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Biosample ID | Series | biosample_type | biosample_lab | genetic_background | stage | Controlled By | anatomical_term | Treatment | Hours Post Fertilization | Mutation Description |
|---|---|---|---|---|---|---|---|---|---|---|
| DCD007061BS | DCD000388SR | tissue | Gomez Lab, CNIC | AB | 90 Days-2 Years | DCD007060BS | heart | cryoinjury | adult | tert-/- |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002080AA | DCD013671BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002461SQ | DCD002473TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002460SQ | DCD002472TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002081AA | DCD013672BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002463SQ | DCD002475TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002462SQ | DCD002474TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Applied Assay ID | Biosample Replicate | Assay |
|---|---|---|
| DCD002082AA | DCD013673BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002465SQ | DCD002477TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002464SQ | DCD002476TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |
| Applied Assay ID | Biosample Replicate | Assay | Controlled By |
|---|---|---|---|
| DCD002083AA | DCD013674BR | RNA-seq_Gomez_Lab_0002AS |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Paired End | Strand | Maximum Read Length | Sequencing Date |
|---|---|---|---|---|---|---|---|---|---|
| DCD002467SQ | DCD002479TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | ✘ | unstranded | — | 07/07/2015 |
| Sequencing ID | Technical Replicate | Sequencing Lab | Platform | Instrument | Chemistry Version | Strand | Sequencing Date |
|---|---|---|---|---|---|---|---|
| DCD002466SQ | DCD002478TR | Gomez Lab, CNIC | Illumina | GAIIx | TruSeq RNA Sample Preparation v2 Kit | unstranded | 07/07/2015 |